西亚试剂：Hippo Pathway in Organ Size Control, Tissue Homeostasis, an

发布时间：2026-02-21

Two decades of studies in multiple model organisms have established the Hippo pathway as a key regulator of organ size and tissue homeostasis. By inhibiting YAP and TAZ transcription co-activators, the Hippo pathway regulates cell proliferation, apoptosis, and stemness in response to a wide range of extracellular and intracellular signals, including cell-cell contact, cell polarity, mechanical cues, ligands of G-protein-coupled receptors, and cellular energy status. Dysregulation of the Hippo pathway exerts a significant impact on cancer development. Further investigation of the functions and regulatory mechanisms of this pathway will help uncovering the mystery of organ size control and identify new targets for cancer treatment

以上资料由西亚试剂：http://www.xiyashiji.com/ 提供

上一篇：西亚试剂：新技术或可对干细胞重编程的不同阶段进行精确定义
下一篇：西亚试剂:顺2,2-二甲基-3-己烯