西亚试剂：Mussel-Inspired Surface Chemistry for Multifunctional Coati

发布时间：2026-02-28

Mussel-Inspired Surface Chemistry for Multifunctional Coatings

Haeshin Lee,1 Shara M. Dellatore,2 William M. Miller,2,3 Phillip B. Messersmith1,3,4*

We report a method to form multifunctional polymer coatings through simple dip-coating of objects in an aqueous solution of dopamine. Inspired by the composition of adhesive proteins in mussels, we used dopamine self-polymerization to form thin, surface-adherent polydopamine films onto a wide range of inorganic and organic materials, including noble metals, oxides, polymers, semiconductors, and ceramics. Secondary reactions can be used to create a variety of ad-layers, including self-assembled monolayers through deposition of long-chain molecular building blocks, metal films by electroless metallization, and bioinert and bioactive surfaces via grafting of macromolecules.

1 Biomedical Engineering, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USA.
2 Chemical and Biological Engineering, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USA.
3 Institute for BioNanotechnology in Medicine, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USA.
4 Materials Science and Engineering, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USA.

* To whom correspondence should be addressed. E-mail:

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