西亚试剂：Single base–resolution methylome of the silkworm reveals a

发布时间：2025-07-14

Single base–resolution methylome of the silkworm reveals a sparse epigenomic map
Hui Xiang,Jingde Zhu,Quan Chen,Fangyin Dai,Xin Li,Muwang Li,Hongyu Zhang,Guojie Zhang,Dong Li,Yang Dong,Li Zhao,Ying Lin,Daojun Cheng,Jian Yu,Jinfeng Sun,Xiaoyu Zhou,Kelong Ma,Yinghua He,Yangxing Zhao,Shicheng Guo,Mingzhi Ye,Guangwu Guo,Yingrui Li,Ruiqiang Li,Xiuqing Zhang,Lijia Ma,Karsten Kristiansen,Qiuhong Guo,
Jianhao Jiang,Stephan Beck,Qingyou Xia,Wen Wang& Jun Wang et al.

 regulation in insects may have effects on diverse biological processes. Here we survey the methylome of a model insect, the silkworm Bombyx mori, at single-base resolution using Illumina high-throughput bisulfite sequencing (MethylC-Seq). We conservatively estimate that 0.11% of genomic cytosines are methylcytosines, all of which probably occur in CG dinucleotides. CG methylation is substantially enriched in gene bodies and is positively correlated with gene expression levels, suggesting it has a positive role in gene transcription. We find that transposable elements, promoters and ribosomal DNAs are hypomethylated, but in contrast, genomic loci matching small RNAs in gene bodies are densely methylated. This work contributes to our understanding of epigenetics in insects, and in contrast to previous studies of the highly methylated genomes of Arabidopsis1 and human2, demonstrates a strategy for sequencing the epigenomes of organisms such as insects that have low levels of methylation.

• 以上资料由西亚试剂：http://www.xiyashiji.com/ 提供此产品的详细信息如密度,含量,分子式,分子量等均可在西亚官网查询   
• 相关产品如溴化汞硝酸亚汞氯化亚汞乙酸苯汞氯化钾汞 碘化汞钾硫氰酸汞硫酸亚汞氧化汞氯化汞碘化汞硝酸汞三氯氧磷三氯化磷碘甲烷二碘甲烷三碘甲烷三氟碘甲烷氘代碘甲烷碘乙烷1,2-二碘乙烷甲酸铷碘化铷溴化铷铬酸铷硫酸铷氟化铷硝酸铷氯化铷碳酸铷硫酸镱 碳酸镱氯化镱硝酸镱氧化镱等均有销售.欢迎订购

上一篇：西亚试剂：氧化松节油酸
下一篇：西亚试剂 :2-甲基噻吩